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Research Areas:
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways:
TLR
IκB/IKK
NF-κB
Interleukin Related
nNOS
5-Lipoxygenase
PGE synthase
SPHK
Innate Immunity
Pulmonary Diseases
SPM
Toll-Like Receptor 7 Ligand II (CAS#226907-52-4 Cat#D945063)
CAS#:
226907-52-4
Formula:
C₁₅H₁₇N₅O₃
Molecular Weight:
315.3
Solubility:
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
Biological Target:
A potential treatment for hepatitis C virus (HCV) is to induce immune cell-derived interferon (IFN) production using synthetic agonists of toll-like receptor 7 (TLR7).
Storage:
Store at -20°C
TLR
$236.00
万
3-Bromo-7-nitroindazole (CAS#74209-34-0 Cat#D910385)
CAS#:
74209-34-0
Formula:
C₇H₄BrN₃O₂
Molecular Weight:
242.03
Solubility:
≥ 10mg/mL in Ethanol
Biological Target:
nNOS inhibitor
Storage:
Store at -20°C
nNOS
$56.00
万
NF-κB Control (CAS#201608-17-5 Cat#D944388)
CAS#:
201608-17-5
Formula:
C₁₂₃H₂₁₅N₃₃O₃₀S
Molecular Weight:
2668.3
Solubility:
DMF: 25 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
Biological Target:
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.
Storage:
Store at -20°C
NF-κB
$142.00
万
PF-543 Citrate (CAS#1415562-83-2 Cat#D916352)
CAS#:
1415562-83-2
Formula:
C₃₃H₃₉NO₁₁S
Molecular Weight:
657.73
Solubility:
≥ 89.4 mg/mL in DMSO, ≥ 28.33 mg/mL in EtOH with ultrasonic and warming, ≥ 51.8 mg/mL in H2O with ultrasonic and warming
Biological Target:
SphK1 inhibitor,potent and cell-permeate
Storage:
Store at -20°C
SPHK
$89.00
万
TLR7-agonist-1 (CAS#1642857-69-9 Cat#D919357)
CAS#:
1642857-69-9
Formula:
C₁₇H₁₆N₆O₂
Molecular Weight:
336.35
Solubility:
DMSO : 160 mg/mL (475.69 mM)
Biological Target:
TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 uM.
Storage:
Store at -20°C
TLR
$163.00
万
MHP (CAS#1104874-94-3 Cat#D919501)
CAS#:
1104874-94-3
Formula:
C₁₆H₂₃NO₄
Molecular Weight:
293.36
Solubility:
Soluble in DMSO
Biological Target:
MHP is an activator of sphingosine kinase (SPHK1)
Storage:
Store at -20°C
SPHK
$105.00
万
K6PC-5 (CAS#756875-51-1 Cat#D949155)
CAS#:
756875-51-1
Formula:
C₁₉H₃₇NO₄
Molecular Weight:
343.5
Solubility:
DMSO: 30 mg/ml
Biological Target:
An SPHK1 activator
Storage:
-20°C
SPHK
$149.00
万
PPM-18 (CAS#65240-86-0 Cat#D916657)
CAS#:
65240-86-0
Formula:
C₁₇H₁₁NO₃
Molecular Weight:
277.3
Solubility:
≥ 27.7mg/mL in DMSO
Biological Target:
NF-κB inhibitor
Storage:
Store at -20°C
NF-κB
$55.00
万
GS-9620 (CAS#1228585-88-3 Cat#D912555)
CAS#:
1228585-88-3
Formula:
C₂₂H₃₀N₆O₂
Molecular Weight:
410.51
Solubility:
≥ 20.55 mg/mL in DMSO, ≥ 9.9 mg/mL in EtOH with ultrasonic and warming
Biological Target:
TLR-7 agonist
Storage:
Store at -20°C
TLR
$101.00
万
Caffeic Acid Phenethyl Ester (CAS#104594-70-9 Cat#D910692)
CAS#:
104594-70-9
Formula:
C₁₇H₁₆O₄
Molecular Weight:
284.31
Solubility:
≥ 28.4mg/mL in DMSO
Biological Target:
NF-κB activation inhibitor
Storage:
Store at -20° C
NF-κB
$66.00
万
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