Dynamic Key Med(DKM)--- Active Compounds
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Research Areas:
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways:
Opioid Receptor
Estrogen/progestogen Receptor
ROR/RAR/RXR
RARγ
Aromatase
Androgen receptor
Thyroid hormone Receptor
Dihydrodaidzein (CAS#17238-05-0 Cat#D910663)
CAS#:
17238-05-0
Formula:
C₁₅H₁₂O₄
Molecular Weight:
256.3
Solubility:
≤0.1mg/ml in ethanol;30mg/ml in DMSO;10mg/ml in dimethyl formamide
Biological Target:
estrogen receptor agonist
Storage:
Store at -20°C
Estrogen/progestogen Receptor
$61.00
万
YM 511 (CAS#148869-05-0 Cat#D916777)
CAS#:
148869-05-0
Formula:
C₁₆H₁₂BrN₅
Molecular Weight:
354.2
Solubility:
<35.42mg/ml in DMSO; <8.86mg/ml in ethanol
Biological Target:
aromatase (CYP19) inhibitor
Storage:
Store at RT
Aromatase
$311.00
万
RD162 (CAS#915087-27-3 Cat#D911957)
CAS#:
915087-27-3
Formula:
C₂₂H₁₆F₄N₄O₂S
Molecular Weight:
476.4
Solubility:
≤30mg/ml in DMSO;30mg/ml in dimethyl formamide
Biological Target:
androgen receptor (AR) antagonist
Storage:
Store at 4°C
Androgen receptor
$52.00
万
Andarine (CAS#401900-40-1 Cat#D913685)
CAS#:
401900-40-1
Formula:
C₁₉H₁₈F₃N₃O₆
Molecular Weight:
441.36
Solubility:
≥ 21mg/mL in DMSO
Biological Target:
Androgen receptor agonist
Storage:
Store at -20°C
Androgen receptor
$62.00
万
Bazedoxifene HCl (CAS#198480-56-7 Cat#D910245)
CAS#:
198480-56-7
Formula:
C₃₀H₃₄N₂O₃.HCl
Molecular Weight:
507.06
Solubility:
≥ 25.35mg/mL in DMSO
Biological Target:
Novel, non-steroidal, indole-based estrogen receptor modulator (SERM)
Storage:
Store at -20°C
Estrogen/progestogen Receptor
$158.00
万
3,3',5'-Triiodo-L-thyronine ( Cat#D910384 ,CAS#5817-39-0)
CAS#:
5817-39-0
Formula:
C₁₅H₁₂I₃NO₄
Molecular Weight:
651
Solubility:
≥ 32.55mg/mL in DMSO
Biological Target:
TRΔα1 activator
Storage:
Store at -20°C
Thyroid hormone Receptor
$62.00
万
MDV3100 (Enzalutamide) (CAS#915087-33-1 Cat#D912385)
CAS#:
915087-33-1
Formula:
C₂₁H₁₆F₄N₄O₂S
Molecular Weight:
464.4
Solubility:
≥ 23.22mg/mL in DMSO
Biological Target:
Androgen receptor antagonist
Storage:
Store at-20°C
Androgen receptor
$78.00
万
MGL-3196 (CAS#920509-32-6 Cat#D918243)
CAS#:
920509-32-6
Formula:
C₁₇H₁₂Cl₂N₆O₄
Molecular Weight:
435.2
Solubility:
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml
Biological Target:
MGL-3196 is an agonist of thyroid hormone receptor β (TRβ; EC50s = 0.21 and 3.74 uM for TRβ and TRα, respectively).
Storage:
Store at -20°C
Thyroid hormone Receptor
$162.00
万
Exemestane (CAS#107868-30-4 Cat#D911813)
CAS#:
107868-30-4
Formula:
C₂₀H₂₄O₂
Molecular Weight:
296.4
Solubility:
≥ 14.82mg/mL in DMSO
Biological Target:
Steroidal aromatase inhibitor,selective and irreversible
Storage:
Store at -20°C
Aromatase
$49.00
万
Anastrozole (CAS#120511-73-1 Cat#D910256)
CAS#:
120511-73-1
Formula:
C₁₇H₁₉N₅
Molecular Weight:
293.37
Solubility:
≥ 14.15mg/mL in DMSO
Biological Target:
Aromatase inhibitor
Storage:
Store at -20°C
Aromatase
$42.00
万
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