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Research Areas:
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways:
EGFR
JAK
STAT
4-methyl Erlotinib (CAS#1346601-52-2 Cat#D912818)
CAS#:
1346601-52-2
Formula:
C₂₃H₂₅N₃O₄
Molecular Weight:
407.5
Solubility:
≤0.25mg/ml in ethanol;25mg/ml in DMSO;50mg/ml in dimethyl formamide
Biological Target:
EGFR inhibitor
Storage:
Store at -20°C
EGFR
$124.00
万
BMS 599626 dihydrochloride (Cat#D914136)
Formula:
C₂₇H₂₇FN₈O₃.₂HCl
Molecular Weight:
603.48
Solubility:
Soluble in DMSO > 10 mM
Biological Target:
EGFR and ErbB2 inhibitor,potent and selective
Storage:
Store at -20°C
EGFR
$114.00
万
HO-3867 (CAS#1172133-28-6 Cat#D916208)
CAS#:
1172133-28-6
Formula:
C₂₈H₃₀F₂N₂O₂
Molecular Weight:
464.55
Solubility:
≥ 18.15mg/mL in DMSO
Biological Target:
STAT3 inhibitor, selective
Storage:
Store at -20°C
STAT
$138.00
万
BIBU 1361 dihydrochloride (CAS#793726-84-8 Cat#D910815)
CAS#:
793726-84-8
Formula:
C₂₂H₂₇ClFN₇.₂HCl
Molecular Weight:
516.87
Solubility:
<51.69mg/ml in H2O; <12.92mg/ml in DMSO
Biological Target:
EGFR inhibitor
Storage:
Store at -20°C
EGFR
$201.00
万
Pyridone 6 (CAS#457081-03-7 Cat#D911525)
CAS#:
457081-03-7
Formula:
C₁₈H₁₆FN₃O
Molecular Weight:
309.34
Solubility:
≥ 15.45 mg/mL in DMSO, ≥ 5.92 mg/mL in EtOH with ultrasonic and warming
Biological Target:
Pan-JAK inhibitor
Storage:
Store at -20°C
JAK
$182.00
万
LY2784544 (CAS#1229236-86-5 Cat#D913848)
CAS#:
1229236-86-5
Formula:
C₂₃H₂₅ClFN₇O
Molecular Weight:
469.94
Solubility:
≥ 23.5 mg/mL in DMSO, ≥ 5.65 mg/mL in EtOH with ultrasonic and warming
Biological Target:
JAK2 inhibitor,highly potent and selective
Storage:
Store at -20°C
JAK
$100.00
万
Gefitinib hydrochloride (CAS#184475-55-6 Cat#D914295)
CAS#:
184475-55-6
Formula:
C₂₂H₂₅Cl₂FN₄O₃
Molecular Weight:
483.36
Solubility:
≥ 6.9 mg/mL in DMSO with gentle warming, ≥ 4.28 mg/mL in H2O with ultrasonic and warming
Biological Target:
Potent EGFR inhibitor
Storage:
Store at -20°C
EGFR
$62.00
万
Tyrphostin B44, (-) enantiomer ( Cat#D912977 ,CAS#133550-32-0)
CAS#:
133550-32-0
Formula:
C₁₈H₁₆N₂O₃
Molecular Weight:
308.34
Solubility:
Soluble in DMSO
Biological Target:
EGFR-kinase inhibitor
Storage:
Store at -20°C
EGFR
$110.00
万
AG-490 (Tyrphostin B42) (CAS#133550-30-8 Cat#D913854)
CAS#:
133550-30-8
Formula:
C₁₇H₁₄N₂O₃
Molecular Weight:
294.3
Solubility:
Soluble in DMSO > 10 mM
Biological Target:
STAT3/EGFR/JAK2/JAK3 inhibitor
Storage:
Store at -20°C
JAK
$36.00
万
Compound 56 (CAS#171745-13-4 Cat#D912837)
CAS#:
171745-13-4
Formula:
C₁₈H₁₈BrN₃O₂
Molecular Weight:
388.3
Solubility:
≥ 16.95mg/mL in DMSO, ≥ 47.6 mg/mL in EtOH with ultrasonic
Biological Target:
REGFR inhibitor
Storage:
Store at -20°C
EGFR
$43.00
万
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