Dynamic Key Med(DKM)--- Active Compounds
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Research Areas:
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways:
Autophagy
Proteasome
DUB
USP/UBP
Aclacinomycin A (CAS#57576-44-0 Cat#D910102)
CAS#:
57576-44-0
Formula:
C₄₂H₅₃NO₁₅
Molecular Weight:
811.87
Solubility:
Soluble in DMSO
Biological Target:
Topoisomerase I and II inhibitor
Storage:
Store at -20°C
Proteasome
$105.00
万
SJB3-019A (CAS#2070015-29-9 Cat#D913401)
CAS#:
2070015-29-9
Formula:
C₁₆H₈N₂O₃
Molecular Weight:
276.25
Solubility:
≥ 10.85mg/mL in DMSO with gentle warming
Biological Target:
Usp1 inhibitor
Storage:
Store at -20°C
USP/UBP
$166.00
万
Dynasore (CAS#304448-55-3 Cat#D910395)
CAS#:
304448-55-3
Formula:
C₁₈H₁₄N₂O₄
Molecular Weight:
322.31
Solubility:
≥ 16.12mg/mL in DMSO
Biological Target:
A dynamin and GTPase inhibitor
Storage:
Store at -20°C
Autophagy
$67.00
万
WP1130 (CAS#856243-80-6 Cat#D910970)
CAS#:
856243-80-6
Formula:
C₁₉H₁₈BrN₃O
Molecular Weight:
384.27
Solubility:
≥ 38.4mg/mL in DMSO
Biological Target:
Deubiquitinase (DUB) inhibitor, Cell permeable
Storage:
Store at -20°C
DUB
$60.00
万
Torin 1 (CAS#1222998-36-8 Cat#D910131)
CAS#:
1222998-36-8
Formula:
C₃₅H₂₈F₃N₅O₂
Molecular Weight:
607.64
Solubility:
<1.22mg/mL in DMSO, ≥ 2.42 mg/mL in EtOH with ultrasonic and warming, <2.39 mg/mL in H2O
Biological Target:
MTOR inhibitor,potent and selective
Storage:
Desiccate at -20°C
Autophagy
$66.00
万
Ciclopirox (CAS#29342-05-0 Cat#D910132)
CAS#:
29342-05-0
Formula:
C₁₂H₁₇NO₂
Molecular Weight:
207.27
Solubility:
≥ 11.2mg/mL in DMSO
Biological Target:
broad-spectrum antifungal agent
Storage:
Store at -20°C
Autophagy
$79.00
万
JNJ-42165279 (CAS#1346528-50-4 Cat#D910133)
CAS#:
1346528-50-4
Formula:
C₁₈H₁₇ClF₂N₄O₃
Molecular Weight:
410.8
Solubility:
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
Biological Target:
FAAH inhibitor
Storage:
Store at -20°C
Autophagy
$136.00
万
SJB2-043 (CAS#63388-44-3 Cat#D917698)
CAS#:
63388-44-3
Formula:
C₁₇H₉NO₃
Molecular Weight:
275.26
Solubility:
≥ 6.7 mg/mL in DMSO
Biological Target:
USP1 inhibitor
Storage:
Store at -20°C
USP/UBP
$213.00
万
PD 151746 (CAS#179461-52-0 Cat#D910561)
CAS#:
179461-52-0
Formula:
C₁₁H₈FNO₂S
Molecular Weight:
237.25
Solubility:
≥ 11.6mg/mL in DMSO
Biological Target:
calpain inhibitor, cell-permeable
Storage:
Desiccate at -20°C
Proteasome
$56.00
万
Tolbutamide (CAS#64-77-7 Cat#D910424)
CAS#:
64-77-7
Formula:
C₁₂H₁₈N₂O₃S
Molecular Weight:
270.35
Solubility:
≥ 10.05mg/mL in DMSO
Biological Target:
first generation potassium channel blocker
Storage:
Store at -20°C
Autophagy
$54.00
万
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