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Research Areas:
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways:
Src
FGFR
RET
VEGFR
EGFR
PDGFR
ITK
c-Met
Spleen Tyrosine Kinase (Syk)
Broad Spectrum Protein Kinase Inhibitor
FAK
IRAK
PKC
ALK
ROS
(E)-FeCP-oxindole (CAS#884338-18-5 Cat#D917800)
CAS#:
884338-18-5
Formula:
C₁₉H₁₅FeNO
Molecular Weight:
329.17
Solubility:
<1.65mg/ml in DMSO
Biological Target:
VEGFR-2 inhibitor
Storage:
Store at -20°C
VEGFR
$458.00
万
PD 173074 (CAS#219580-11-7 Cat#D917943)
CAS#:
219580-11-7
Formula:
C₂₈H₄₁N₇O₃
Molecular Weight:
523.67
Solubility:
≥ 26.1835mg/mL in DMSO, ≥ 108.4 mg/mL in EtOH with ultrasonic
Biological Target:
FGFR inhibitor
Storage:
Store at 4°C
FGFR
$46.00
万
BLU-554 (CAS#1707289-21-1 Cat#D919075)
CAS#:
1707289-21-1
Formula:
C₂₄H₂₄Cl₂N₄O₄
Molecular Weight:
503.38
Solubility:
DMSO : ≥ 25 mg/mL (49.66 mM)
Biological Target:
BLU-554 is a potent fibroblast growth factor receptor 4 (FGFR4) inhibitor.
Storage:
Store at -20°C
FGFR
$56.00
万
TAK-659 hydrochloride (CAS#1952251-28-3 Cat#D919344)
CAS#:
1952251-28-3
Formula:
C₁₇H₂₂ClFN₆O
Molecular Weight:
380.85
Solubility:
DMSO : < 1 mg/mL (insoluble or slightly soluble);H2O : 2 mg/mL (5.25 mM; ultrasonic and adjust pH to 3 with HCl)
Biological Target:
TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM.
Storage:
Store at -20°C
Spleen Tyrosine Kinase (Syk)
$78.00
万
Ki8751 (CAS#228559-41-9 Cat#D911666)
CAS#:
228559-41-9
Formula:
C₂₄H₁₈F₃N₃O₄
Molecular Weight:
469.41
Solubility:
≥ 23.45mg/mL in DMSO
Biological Target:
VEGFR-2 inhibitor,potent and selective
Storage:
Store at -20°C
VEGFR
$39.00
万
KX1-004 (CAS#518058-84-9 Cat#D910523)
CAS#:
518058-84-9
Formula:
C₁₆H₁₃FN₂O₂
Molecular Weight:
284.29
Solubility:
≥ 10.1mg/mL in DMSO
Biological Target:
Pp60c-src inhibitor
Storage:
Store at -20°C
Src
$264.00
万
ASP5878 (CAS#1453208-66-6 Cat#D934476)
CAS#:
1453208-66-6
Formula:
C₁₈H₁₉F₂N₅O₄
Molecular Weight:
407.37
Solubility:
DMSO : ≥ 250 mg/mL (613.69 mM);H2O : < 0.1 mg/mL (insoluble)
Storage:
Store at -20°C
FGFR
$506.00
万
Vandetanib (ZD6474) (CAS#443913-73-3 Cat#D915022)
CAS#:
443913-73-3
Formula:
C₂₂H₂₄BrFN₄O₂
Molecular Weight:
475.35
Solubility:
≥ 11.9mg/mL in DMSO with gentle warming
Biological Target:
VEGFR2/EGFR antagonist
Storage:
Store at -20°C
VEGFR
$79.00
万
Lenvatinib (E7080) (CAS#417716-92-8 Cat#D915454)
Synonym:
Lenvatinib free base; E7080; E-7080; E 7080; ER-203492-00; Lenvatinib; Lenvatinib mesylate; trade name Lenvima
Purity:
>98%
CAS#:
417716-92-8
Formula:
C₂₁H₁₉ClN₄O₄
Molecular Weight:
426.85
Solubility:
≥ 21.35mg/mL in DMSO
Biological Target:
VEGFR2:4 nM (IC50) VEGFR3:5.2 nM (IC50)
Storage:
Store at 4°C, protect from light
VEGFR
$84.00
万
ON123300 (CAS#1357470-29-1 Cat#D915607)
CAS#:
1357470-29-1
Formula:
C₂₄H₂₇N₇O
Molecular Weight:
429.52
Solubility:
≥ 21.5mg/mL in DMSO with gentle warming
Biological Target:
multi-targeted kinase inhibitor,inhibits CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn
Storage:
Store at -20°C
FGFR
$88.00
万
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