Dynamic Key Med(DKM)--- Active Compounds
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Research Areas：
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways：
Histone Methyltransferase
Histone Demethylases
Histone Acetyltransferases
DNA Methyltransferase
Bromodomain
Epigenetic Reader Domain
MS023 （CAS#1831110-54-3 Cat#D910099）
CAS#：
1831110-54-3
Formula：
C₁₇H₂₅N₃O
Molecular Weight：
287.4
Solubility：
≥ 28.7mg/mL in DMSO
Biological Target：
type I PRMTs inhibitor
Storage：
Store at -20°C
Histone Methyltransferase
$85.00
万
JIB-04 （CAS#199596-05-9 Cat#D915603）
CAS#：
199596-05-9
Formula：
C₁₇H₁₃ClN₄
Molecular Weight：
308.76
Solubility：
≥ 14.2mg/mL in DMSO
Biological Target：
Jumonji histone demethylase inihibitor
Storage：
Store at -20° C
Histone Demethylases
$121.00
万
I-CBP 112 （Cat#D917944）
Formula：
C₂₇H₃₆N₂O₅
Molecular Weight：
468.59
Solubility：
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Biological Target：
CBP/EP300 bromodomain inhibitor
Storage：
Store at 4°C
Bromodomain
$265.00
万
Nanaomycin C （CAS#58286-55-8 Cat#D910243）
CAS#：
58286-55-8
Formula：
C₁₆H₁₅NO₅
Molecular Weight：
301.294
Solubility：
Soluble in Methanol
Biological Target：
Amide of nanaomycin A
Storage：
Store at -20°C
DNA Methyltransferase
$265.00
万
CPI-637 （CAS#1884712-47-3 Cat#D910382）
CAS#：
1884712-47-3
Formula：
C₂₂H₂₂N₆O
Molecular Weight：
386.45
Solubility：
≥ 19.3mg/mL in DMSO with gentle warming
Biological Target：
CBP/EP300 bromodomain inhibitor
Storage：
Store at -20°C
Histone Acetyltransferases
$93.00
万
BAZ2-ICR （CAS#1665195-94-7 Cat#D915175）
CAS#：
1665195-94-7
Formula：
C₂₀H₁₉N₇
Molecular Weight：
357.41
Solubility：
<35.74mg/ml in DMSO; <35.74mg/ml in ethanol
Biological Target：
Selective BAZ2 bromodomain inhibitor
Storage：
Store at -20°C
Histone Acetyltransferases
$70.00
万
MZ1 （CAS#1797406-69-9 Cat#D918729）
CAS#：
1797406-69-9
Formula：
C₄₉H₆₀ClN₉O₈S₂
Molecular Weight：
1002.6
Solubility：
DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL,Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
Biological Target：
MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4).
Storage：
Store at -20°C
Bromodomain
$140.00
万
LP99 （CAS#1808951-93-0 Cat#D918731）
CAS#：
1808951-93-0
Formula：
C₂₆H₃₀ClN₃O₄S
Molecular Weight：
516.1
Solubility：
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2) (1:9): 0.1 mg/ml
Biological Target：
LP99 is a potent inhibitor of the bromodomain containing proteins BRD7 and BRD9 that binds with Kd values of 99 and 909 nM, respectively, as determined by isothermal titration calorimetry.
Storage：
Store at -20°C
Bromodomain
$75.00
万
Trichostatin C （CAS#68676-88-0 Cat#D945080）
CAS#：
68676-88-0
Formula：
C₂₃H₃₂N₂O₈
Molecular Weight：
464.5
Solubility：
DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
Biological Target：
Trichostatin C is a glycosylated derivative of trichostatin A, the antifungal antibiotic that reversibly inhibits histone deacetylase.
Storage：
Store at -20°C
Histone Demethylases
$558.00
万
AS8351 （CAS#796-42-9 Cat#D917820）
CAS#：
796-42-9
Formula：
C₁₇H₁₃N₃O₂
Molecular Weight：
291.3
Solubility：
≥ 29.1mg/mL in DMSO
Biological Target：
histone demethylase inhibitor
Storage：
Store at -20°C
Histone Demethylases
$58.00
万
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