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Research Areas:
Proteases
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Signaling Pathways:
MDM2/MDMX
Other Apoptosis
PAR4
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PD-1/PD-L1
Others
TNF-alpha
Ferroptosis
Ras
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PERK
PKD
PFKFB
Bcl-6
Heme Oxygenase
Pyroptosis
Survivin
Nur77
ASK
cytohesin
DAPK
TRADD
SNS-314 Mesylate (CAS#1146618-41-8 Cat#D913837)
CAS#:
1146618-41-8
Formula:
C₁₈H₁₅ClN₆OS₂.CH₄O₃S
Molecular Weight:
527.04
Solubility:
≥ 26.35 mg/mL in DMSO
Biological Target:
Aurora A/B/C kinases inhibitor, potent and selective
Storage:
Store at -20°C
Other Apoptosis
$75.00
万
TAK-901 (CAS#934541-31-8 Cat#D911085)
CAS#:
934541-31-8
Formula:
C₂₈H₃₂N₄O₃S
Molecular Weight:
504.64
Solubility:
≥ 25.25 mg/mL in DMSO
Biological Target:
Novel Aurora A/B inhibitor
Storage:
Store at -20°C
Other Apoptosis
$102.00
万
Ac-DEVD-CMK (CAS#285570-60-7 Cat#D910951)
CAS#:
285570-60-7
Formula:
C₂₁H₃₁ClN₄O₁₁
Molecular Weight:
551
Solubility:
≤50mg/ml in DMSO
Biological Target:
cell-permeable, and irreversible inhibitor of caspase
Storage:
Store at -20°C
Caspase
$133.00
万
NSC 66811 (CAS#6964-62-1 Cat#D913687)
CAS#:
6964-62-1
Formula:
C₂₃H₂₀N₂O
Molecular Weight:
340.42
Solubility:
≥ 34 mg/mL in DMSO, ≥ 3.82 mg/mL in EtOH with ultrasonic and warming
Biological Target:
MDM2 inhibitor
Storage:
Store at -20°C
MDM2/MDMX
$67.00
万
Nutlin-3 (CAS#890090-75-2 Cat#D916051)
CAS#:
890090-75-2
Formula:
C₃₀H₃₀Cl₂N₄O₄
Molecular Weight:
581.5
Solubility:
≥ 58.2 mg/mL in DMSO, ≥ 5.69 mg/mL in EtOH with ultrasonic
Biological Target:
MDM2 antagonist,inhibits MDM2-p53 interaction
Storage:
Store at -20°C
MDM2/MDMX
$72.00
万
ERB 041 (CAS#524684-52-4 Cat#D910389)
CAS#:
524684-52-4
Formula:
C₁₅H₁₀FNO₃
Molecular Weight:
271.24
Solubility:
DMSO: 25 mg/ml
Biological Target:
ERβ agonist
Storage:
Store at -20°C
Other Apoptosis
$152.00
万
BMS-1001 hydrochloride (CAS#2113650-04-5 Cat#D938740)
CAS#:
2113650-04-5
Formula:
C₃₅H₃₅ClN₂O₇
Molecular Weight:
631.11
Solubility:
DMSO: 12.5 mg/mL (19.81 mM)
Storage:
Store at -20°C
PD-1/PD-L1
$79.00
万
BMS-8 (CAS#1675201-90-7 Cat#D942957)
CAS#:
1675201-90-7
Formula:
C₂₇H₂₈BrNO₃
Molecular Weight:
494.4
Solubility:
Methanol: slightly soluble
Biological Target:
BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
Storage:
Store at -20°C
PD-1/PD-L1
$85.00
万
PD-1-IN-1 (CAS#1673534-76-3 Cat#D919225)
CAS#:
1673534-76-3
Formula:
C₁₂H₂₀N₆O₇
Molecular Weight:
360.32
Solubility:
DMSO : 28.5 mg/mL (79.10 mM)
Biological Target:
PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
Storage:
Store at -20°C
PD-1/PD-L1
$394.00
万
MLN8237 (Alisertib) (CAS#1028486-01-2 Cat#D912690)
CAS#:
1028486-01-2
Formula:
C₂₇H₂₀ClFN₄O₄
Molecular Weight:
518.92
Solubility:
≥ 25.9 mg/mL in DMSO
Biological Target:
Aurora A Kinase inhibitor, Potent and selective
Storage:
Store at -20°C
Other Apoptosis
$104.00
万
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