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Research Areas：
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
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Peptides
Default
Research Grade Biosimilar
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PROTAC
Stem Cell
Signaling Pathways：
MDM2/MDMX
Other Apoptosis
PAR4
Bcl-2
Caspase
Apoptosis Inducers
p53
PD-1/PD-L1
Others
TNF-alpha
Ferroptosis
Ras
c-RET
RIP kinase
IAP
Myc
OXPHOS
FKBP
Thymidylate Synthase
PERK
PKD
PFKFB
Bcl-6
Heme Oxygenase
Pyroptosis
Survivin
Nur77
ASK
cytohesin
DAPK
TRADD
SNS-314 Mesylate （CAS#1146618-41-8 Cat#D913837）
CAS#：
1146618-41-8
Formula：
C₁₈H₁₅ClN₆OS₂.CH₄O₃S
Molecular Weight：
527.04
Solubility：
≥ 26.35 mg/mL in DMSO
Biological Target：
Aurora A/B/C kinases inhibitor, potent and selective
Storage：
Store at -20°C
Other Apoptosis
$75.00
万
TAK-901 （CAS#934541-31-8 Cat#D911085）
CAS#：
934541-31-8
Formula：
C₂₈H₃₂N₄O₃S
Molecular Weight：
504.64
Solubility：
≥ 25.25 mg/mL in DMSO
Biological Target：
Novel Aurora A/B inhibitor
Storage：
Store at -20°C
Other Apoptosis
$102.00
万
Ac-DEVD-CMK （CAS#285570-60-7 Cat#D910951）
CAS#：
285570-60-7
Formula：
C₂₁H₃₁ClN₄O₁₁
Molecular Weight：
551
Solubility：
≤50mg/ml in DMSO
Biological Target：
cell-permeable, and irreversible inhibitor of caspase
Storage：
Store at -20°C
Caspase
$133.00
万
NSC 66811 （CAS#6964-62-1 Cat#D913687）
CAS#：
6964-62-1
Formula：
C₂₃H₂₀N₂O
Molecular Weight：
340.42
Solubility：
≥ 34 mg/mL in DMSO, ≥ 3.82 mg/mL in EtOH with ultrasonic and warming
Biological Target：
MDM2 inhibitor
Storage：
Store at -20°C
MDM2/MDMX
$67.00
万
Nutlin-3 （CAS#890090-75-2 Cat#D916051）
CAS#：
890090-75-2
Formula：
C₃₀H₃₀Cl₂N₄O₄
Molecular Weight：
581.5
Solubility：
≥ 58.2 mg/mL in DMSO, ≥ 5.69 mg/mL in EtOH with ultrasonic
Biological Target：
MDM2 antagonist,inhibits MDM2-p53 interaction
Storage：
Store at -20°C
MDM2/MDMX
$72.00
万
ERB 041 （CAS#524684-52-4 Cat#D910389）
CAS#：
524684-52-4
Formula：
C₁₅H₁₀FNO₃
Molecular Weight：
271.24
Solubility：
DMSO: 25 mg/ml
Biological Target：
ERβ agonist
Storage：
Store at -20°C
Other Apoptosis
$152.00
万
BMS-1001 hydrochloride （CAS#2113650-04-5 Cat#D938740）
CAS#：
2113650-04-5
Formula：
C₃₅H₃₅ClN₂O₇
Molecular Weight：
631.11
Solubility：
DMSO: 12.5 mg/mL (19.81 mM)
Storage：
Store at -20°C
PD-1/PD-L1
$79.00
万
BMS-8 （CAS#1675201-90-7 Cat#D942957）
CAS#：
1675201-90-7
Formula：
C₂₇H₂₈BrNO₃
Molecular Weight：
494.4
Solubility：
Methanol: slightly soluble
Biological Target：
BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
Storage：
Store at -20°C
PD-1/PD-L1
$85.00
万
PD-1-IN-1 （CAS#1673534-76-3 Cat#D919225）
CAS#：
1673534-76-3
Formula：
C₁₂H₂₀N₆O₇
Molecular Weight：
360.32
Solubility：
DMSO : 28.5 mg/mL (79.10 mM)
Biological Target：
PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
Storage：
Store at -20°C
PD-1/PD-L1
$394.00
万
MLN8237 (Alisertib) （CAS#1028486-01-2 Cat#D912690）
CAS#：
1028486-01-2
Formula：
C₂₇H₂₀ClFN₄O₄
Molecular Weight：
518.92
Solubility：
≥ 25.9 mg/mL in DMSO
Biological Target：
Aurora A Kinase inhibitor, Potent and selective
Storage：
Store at -20°C
Other Apoptosis
$104.00
万
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